Good Magazine which just opened a new location and event space on Beverly donates 100% of its subscription price to the nonprofit of your choice. (And it's a great magazine).
826LA is a non-profit organization dedicated to supporting students ages 6 to 18 with their creative and expository writing skills, and to helping teachers inspire their students to write. Started up in Northern California by Dave Eggers and friends this space is committed to helping students express themselves. You can donate money, but posters and books from their time travel mart or donate your time to help tutor students.
Velaslvaysay Panorama is an old movie theatre turned exhibition hall, theatre and garden dedicated to the production and presentation of unusual visual experiences, including those of the 360-degree variety. Join their Enthusiast Society and help keep the arts alive.
[Images: Poster from 826LA, Stephen Colbert in the latest issue of Good, Machine Project's Birds for Chris Burden from Katherine Guillen, the outside of the Panorama]