Turkey in general was history plus leisure, wrapped in a bow of excellent (and kid-friendly) food, amazing hospitality, and a distinct lack of touristy feel. It was unlike any other places I have visited, in that you never really felt like you were on a tourist path. Even in a place like Ephesus.
In addition to Ephesus, I would highly recommend Olympos for families. Beautiful beaches, more ruins, and the mythical Chimaera all make for an amazing time.
Best Tip for Traveling with Kids: Slow down. Where pre-kid you'd go from place to place, with children it is great to stay at least a few days in one spot. Pick a good base with lots of activities nearby. If someone needs a nap or no one feels like leaving the pool one afternoon, you don't feel like you are missing out.
Favorite Way to Make it Feel Like Home: Well, if you wanted to be at home, you wouldn't be traveling, right? But, of course there are those little things that make everyone feel happier. I like having a family-friendly base, which means a hotel or B&B or house swap where we don't have to worry about imposing or just being ourselves.
An Item you MUST Take With You While Traveling: Lots of sunscreen, hats, water bottles, a few small toys, and some Magic Treehouse books. And a camera!