Best Design Destinations in Istanbul?

Good Questions

Q. So actually this is my own question. We're heading to Turkey next week for a long anticipated family vacation, and we have a number of days in Istanbul. I know it's a great design city for both ancient and modern, but I know nothing.

Could anyone tell me what are the MUST see design destinations in the city? Which areas? Even great food? Heck I'll take it all. I haven't had a vacation like this in a long time!

Thanks in advance, Maxwell