After looking around, my dining room seemed to be the best bet. It gets minimal use and (confession) this would certainly be a lot better than using it as a dumping ground for mail. In fact, I'd previously considered transforming it into an office/den but scrapped the project as too costly for now.
Deciding how to orient the dining table/desk was the key to figuring out the whole space. The chandelier hangs too low to walk under. Then I came across a photo that provided inspiration; putting the table/desk at an angle solved my problem. Plus, it lets me face outwards instead of looking at a wall all day. After that it was just a matter of gathering up items from around the house. A pile of favorite and inspirational design books, a vase, a tray. I'm starting to put together my taxes so my financial folder is on my desk. Later, maybe I'll add a desk lamp or move my fishbowl to the desk's corner but for now I'm ready for work!
Images: 1, 3 & 4: Abby Stone; 2: The Apartment Therapy's Big Book of Small, Cool Spaces