E's mom, a veteran of several large moves while raising 3 boys, had some advice that made all the difference. She said: get the kitchen entirely unpacked: no boxes, no delayed decisions, get it functional that first night and the whole rest of the unpacking and moving will be breeze by because you won't be having to order out, you won't have boxes on the counters, you won't feel crazy every time you walk into this one room.
She helped me that night and we got everything completely unpacked and put away. It made such a huge difference to be able to get up in the morning and make breakfast and coffee like a normal day.
What's the First Thing You Unpack?