Apparently, the brain behind SafeType designed the keyboard around the premise of an "orthopedically neutral" posture. He figured out how human hands rest naturally on a desk, and then designed the gadget with the intention to bring the keys to your hands.
A review of the keyboard on Yahoo! says that this product is only a go for those who "don't get easily frustrated." We can see how that might be true. While SafeType is probably effective in reducing finger and wrist strains on your hands during computer use, it is not worth a dime if you just decide to chuck it across the room after the ump-teenth time you type "O hsre thos srupod rhimg!" ("I hate this stupid thing!"). Probably a good rule of thumb not to buy anything that requires the use of mirrors to fully see what you're doing.
Besides that, we can't see how anybody would make this work in any space, no matter how sterile your cubicle may be. If you're still in need of some wrist support, a chance on one of these improvements to the basic keyboard instead: